Thursday 5 December 2013

What is a biological model..?!

( Not to confused with model organism)

Models represent aspects, a term that denotes a coherent set of properties or phenomena of biological interest. The aspect anchors the model in the real world. We establish a correspondence through an ontology, an explicit formal specification of how to represent the objects, concepts, and other entities assumed to exist in the biological domain being studied and the relationships that hold among them. The model and appropriate elements must then be linked to elements in the ontology.


Assumptions condition or determine the relationship between models and the aspects they represent. Assumptions underpin model construction,
constitute the rationale for the model, and must be precisely documented and connected to the model for it to have meaning beyond the immediate use to which it has been put.
Experimental biologists make observations about phenomena of biological interest. Classically, these observations are used to validate interpretations
derived from models. Commonly, however, models yield interpretations that prompt further observations or, when compared with observations, question the validity of the assumptions. Researchers document the observations in the scientific literature and in data resources associated with the experiments.



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